Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810012Generated: October 26, 2026

4-Chlorophenethyl iodide → HCID 178460753, compound

https://huagongshe.com/reaction/1810012

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorophenethyl iodideHCID 22314719—
ReactantEthyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoateHCID 57481427—
ReactantHCID 178460750HCID 178460750—
ProductHCID 178460753HCID 178460753—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of 2-Methyl-2-{2-[3-(trans-4-methyl-cyclohexyl)-3-phenethyl-ureido]-thiazol-5-ylsulfanyl}-propionic acid using 1-chloro-4-(2-iodo-ethyl)-benzene (J. Med. Chem. 1998, 41, 3, 358-378) and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362049B2
Source datasetuspto-grants-2013_01
ORD IDord-677a706dd7024c7fb3da9c7147888df6
Source noteuspto-grants-2013_01