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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810016Generated: November 1, 2026

3-Chloro-5-fluorobenzeneethanol → HCID 178460755, compound

https://huagongshe.com/reaction/1810016

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-5-fluorobenzeneethanolHCID 2757560—
ReactantEthyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoateHCID 57481427—
ReactantHCID 178490373HCID 178490373—
ProductHCID 178460755HCID 178460755—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of 2-{2-[3-[2-(3-fluoro-4-methoxy-phenyl)-ethyl]-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2-methyl-propionic acid using 1-(2-hydroxy-ethyl)-3-chloro-5-fluoro-benzene and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362049B2
Source datasetuspto-grants-2013_01
ORD IDord-395389e0ca7b413e84707ea76b60de23
Source noteuspto-grants-2013_01