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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810033Generated: October 30, 2026

3-(3-Trifluoromethylphenyl)propanoic acid → HCID 178461314, compound

https://huagongshe.com/reaction/1810033

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Trifluoromethylphenyl)propanoic acidHCID 2777683—
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
ReactantHCID 178461316HCID 178461316—
ProductHCID 178461314HCID 178461314—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of {2[-3-[3-(3-Chloro-phenyl)-propyl]-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid using 3-(3-trifluoromethyl-phenyl)-propionic acid and (2-aminothiazol-5-ylsulfanyl)acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362049B2
Source datasetuspto-grants-2013_01
ORD IDord-7c76afcf114d4363ac6a4d37529b81b2
Source noteuspto-grants-2013_01