HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 181006Generated: October 31, 2026
1,4-Dioxane → 4-{3-[4-(4-Cyclopropylcarbamoyl-benzo[b]thiophen-2-yl)-5-fluoropyrimidin-2-ylamino]-propyl}-piperidine-1-carboxylic acid tert-butyl ester
https://huagongshe.com/reaction/181006
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | tert-Butyl 4-(3-aminopropyl)piperidine-1-carboxylate | HCID 22990164 | — |
| Reactant | 2-(2-Chloro-5-fluoropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamide | HCID 86625376 | — |
| Product | 4-{3-[4-(4-Cyclopropylcarbamoyl-benzo[b]thiophen-2-yl)-5-fluoropyrimidin-2-ylamino]-propyl}-piperidine-1-carboxylic acid tert-butyl ester | HCID 68906207 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
|---|
| ORD ID | ord-0c2273ce708943549acaa0607c587d43 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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