HCID 178461316, compound → HCID 178496613, compound

HRID 1810091Notes

Reaction equation

HRID 1810091 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][CH2:10][N:11]([C@H:25]2[CH2:30][CH2:29][C@H:28](C)[CH2:27][CH2:26]2)[C:12](=[O:24])[NH:13][C:14]2[S:15][C:16]([S:19][CH2:20][C:21]([OH:23])=[O:22])=[CH:17][N:18]=2)[CH:5]=[CH:6][CH:7]=1.[CH3:32][O:33][C@H]1CC[C@H](N)CC1>>[CH3:32][O:33][C@H:28]1[CH2:29][CH2:30][C@H:25]([N:11]([CH2:10][CH2:9][CH2:8][C:4]2[CH:3]=[CH:2][CH:7]=[CH:6][CH:5]=2)[C:12](=[O:24])[NH:13][C:14]2[S:15][C:16]([S:19][CH2:20][C:21]([OH:23])=[O:22])=[CH:17][N:18]=2)[CH2:26][CH2:27]1

Participants

3

Reactant 2

HCID 178461316HCID 178461316, compoundHCID 178496609HCID 178496609, compound

Product 1

HCID 178496613HCID 178496613, compound

Procedure

The compound was prepared following an analogous procedure to the one described for the synthesis of {2-[-3-[3-(3-chloro-phenyl)-propyl]-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid using trans-4-methoxy-cyclohexylamine,

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-db78790fe4e3460899717424cce7f730
Source dataset
uspto-grants-2013_01
Patent number
US08362049B2

Reaction notes

Loading…