Acetyl chloride → HCID 66608994, compound

HRID 1810249Notes

Reaction equation

HRID 1810249 reaction equation
[CH3:1][O:2][C:3](=[O:34])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH2:23][NH:24][C@H:25]2[C:33]3[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH2:27][CH2:26]2)[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[C:35](Cl)(=[O:37])[CH3:36]>>[CH3:1][O:2][C:3](=[O:34])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:20])[F:21])=[CH:15][C:14]=2[CH2:23][N:24]([C:35](=[O:37])[CH3:36])[C@H:25]2[C:33]3[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH2:27][CH2:26]2)[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 66607232HCID 66607232, compound

Product 1

HCID 66608994HCID 66608994, compound

Procedure

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: [2′-((R)-indan-1-ylaminomethyl)-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl ester and acetyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d9c3a70cfa8b45a3b627ae654e7b9775
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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