Acetyl chloride → HCID 66608078, compound

HRID 1810259Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:31])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH2:23][NH:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[C:32](Cl)(=[O:34])[CH3:33]>>[CH3:1][O:2][C:3](=[O:31])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH2:23][N:24]([C:32](=[O:34])[CH3:33])[C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 66606672HCID 66606672, compound

Product 1

HCID 66608078HCID 66608078, compound

Procedure

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (6-methoxy-2′-phenylaminomethyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and acetyl chloride.

Workup

customPrepared

Sources & evidence

ORD record: ord-3621a5c6923b400eb3fb8a66dc0ac05c
Source dataset: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08362044B2

Reaction notes

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