Ethanol → Ethyl 2-(3-bromo-4-hydroxyphenyl)acetate

HRID 1810291Notes

Reaction equation

HRID 1810291 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[CH:6][C:7]=1[OH:8].S(=O)(=O)(O)O.[CH3:18][CH2:19]O>>[CH2:18]([O:11][C:10](=[O:12])[CH2:9][C:4]1[CH:5]=[CH:6][C:7]([OH:8])=[C:2]([Br:1])[CH:3]=1)[CH3:19]

Participants

4

Reactant 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 27696283-Bromo-4-hydroxyphenylacetic acid

Product 1

HCID 18620106Ethyl 2-(3-bromo-4-hydroxyphenyl)acetate

Procedure

(3-Bromo-4-hydroxy-phenyl)-acetic acid (5.6 mmol) in EtOH (20 mL) was treated with sulfuric acid (1 mL) and stirred at room temperature over the weekend. The mixture was concentrated to give the title compound.

Workup

  1. concentrationThe mixture was concentrated

Sources & evidence

ORD record
ord-f995a04c59ef4c32afcaf8aeff6f81c5
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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