HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-5-nitrobenzoic acid → (2-Bromo-5-nitrophenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-5-nitrobenzoic acid | HCID 243025 | — |
| Reactant | Borane;tetrahydrofuran | HCID 2723981 | — |
| Product | (2-Bromo-5-nitrophenyl)methanol | HCID 18671373 | — |
Reaction Steps
To 2-bromo-5-nitrobenzoic acid (5 g, 20 mmol) at 0° C. was added borane tetrahydrofuran complex (1M in THF; 200 mL, 200 mmol), and the reaction was stirred at room temperature overnight. The mixture was quenched with 1N aqueous HCl to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362044B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-d6df3095331148b58a4c4cecca8e05b5 |
| Source note | uspto-grants-2013_01 |