5-Methoxy-2-formylphenylboronic acid → (2'-Formyl-6,5'-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester

HRID 1810305Notes

Reaction equation

HRID 1810305 reaction equation
[CH3:1][O:2][C:3](=[O:14])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7](Br)[CH:6]=1.[CH:15]([C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][C:18]=1B(O)O)=[O:16]>>[CH3:1][O:2][C:3](=[O:14])[CH2:4][C:5]1[CH:6]=[C:7]([C:22]2[CH:21]=[C:20]([O:23][CH3:24])[CH:19]=[CH:18][C:17]=2[CH:15]=[O:16])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 27343665-Methoxy-2-formylphenylboronic acidHCID 12717575Methyl 2-(3-bromo-4-methoxyphenyl)acetate

Product 1

HCID 58148902(2'-Formyl-6,5'-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: (3-bromo-4-methoxy-phenyl)-acetic acid methyl ester and 2-formyl-5-methoxyphenylboronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fe1076a9821746039eeac189344c4c08
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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