Benzenepropanoyl chloride → (4'-(6-Ethoxy-pyridin-3-yl)-2'-{[ethyl-(3-phenyl-propionyl)-amino]-methyl}-6-methoxy-biphenyl-3-yl)-acetic acid ethyl ester

Participants

Role	Name	HCID	Charge
Reactant	Benzenepropanoyl chloride	HCID 64801	—
Reactant	[4'-(6-Ethoxy-pyridin-3-yl)-2'-ethylaminomethyl-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester hydrochloride	HCID 66958971	—
Product	(4'-(6-Ethoxy-pyridin-3-yl)-2'-{[ethyl-(3-phenyl-propionyl)-amino]-methyl}-6-methoxy-biphenyl-3-yl)-acetic acid ethyl ester	HCID 58149304	—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: [4′-(6-ethoxy-pyridin-3-yl)-2′-ethylaminomethyl-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester, hydrochloride and hydrocinnamoyl chloride.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08362044B2
Source dataset	uspto-grants-2013_01
ORD ID	ord-2399742eeff54243918abceca5f92273
Source note	uspto-grants-2013_01