Dichloromethane → 1-(Quinolin-5-ylamino)-3-[1-(5-fluoro-2-hydroxyphenyl)cycloprop-1-yl]-2-(trifluoromethyl)propan-2-ol
Reaction equation
[B:32]([Br:33])([Br:34])[Br:35].[Cl:36][CH2:37][Cl:38].[n:1]1[cH:2][cH:3][cH:4][c:5]2[c:6]([NH:11][CH2:12][C:13]([CH2:14][C:15]3([c:18]4[c:19]([O:25][CH3:26])[cH:20][cH:21][c:22]([F:24])[cH:23]4)[CH2:16][CH2:17]3)([OH:27])[C:28]([F:29])([F:30])[F:31])[cH:7][cH:8][cH:9][c:10]12>>[n:1]1[cH:2][cH:3][cH:4][c:5]2[c:6]([NH:11][CH2:12][C:13]([CH2:14][C:15]3([c:18]4[c:19]([OH:25])[cH:20][cH:21][c:22]([F:24])[cH:23]4)[CH2:16][CH2:17]3)([OH:27])[C:28]([F:29])([F:30])[F:31])[cH:7][cH:8][cH:9][c:10]12Participants
4
Sources & evidence
- ORD record
- ord-8388a2c96e8540dba9a0e02b86b44934
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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