Acetyl chloride → HCID 66607312, compound

HRID 1810333Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:29])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH2:23][NH:24][CH:25]2[CH2:28][CH2:27][CH2:26]2)[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[C:30](Cl)(=[O:32])[CH3:31]>>[CH3:1][O:2][C:3](=[O:29])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:20])[F:21])=[CH:15][C:14]=2[CH2:23][N:24]([C:30](=[O:32])[CH3:31])[CH:25]2[CH2:26][CH2:27][CH2:28]2)[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 66607817HCID 66607817, compound

Product 1

HCID 66607312HCID 66607312, compound

Procedure

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-cyclobutylaminomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and acetyl chloride.

Workup

customPrepared

Sources & evidence

ORD record: ord-4a88fa795b514bb3a9631f5545e0a2fb
Source dataset: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08362044B2

Reaction notes

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