Phosgene → 4-Fluorobenzyl carbonochloridate

HRID 1810346Notes

Reaction equation

HRID 1810346 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][OH:7])=[CH:4][CH:3]=1.[C:10](Cl)([Cl:12])=[O:11]>>[Cl:12][C:10]([O:7][CH2:6][C:5]1[CH:8]=[CH:9][C:2]([F:1])=[CH:3][CH:4]=1)=[O:11]

Participants

3

Reactant 2

HCID 6371PhosgeneHCID 680224-Fluorobenzylic alcohol

Product 1

HCID 132929264-Fluorobenzyl carbonochloridate

Procedure

Prepared according to the procedure described in Example 56, Step 1, using the following starting materials: 4-fluorobenzyl alcohol and phosgene (20% in toluene).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2cce0256f76749fab977c960db0caa05
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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