Phosgene → 1-(4-Chlorophenyl)ethyl Chloroformate

HRID 1810352Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([OH:10])[CH3:9])=[CH:4][CH:3]=1.[C:11](Cl)([Cl:13])=[O:12]>>[Cl:13][C:11]([O:10][CH:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)[CH3:9])=[O:12]

Participants

Reactant 2

HCID 6371Phosgene

HCID 18825Benzenemethanol, 4-chloro-alpha-methyl-

Product 1

HCID 574588031-(4-Chlorophenyl)ethyl Chloroformate

Procedure

Prepared according to the procedure described in Example 56, Step 1, using the following starting materials: 1-(4-chlorophenyl)ethanol and phosgene (20% in toluene).

Workup

customPrepared

Sources & evidence

ORD record: ord-509a9f278caf40348622f843202d2ffb
Source dataset: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08362044B2

Reaction notes

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