2-Bromo-5-(trifluoromethyl)benzaldehyde → HCID 86651114, compound

HRID 1810357Notes

Reaction equation

HRID 1810357 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH:5]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[C:9](B2OC(C)(C)C(C)(C)O2)[CH:8]=1)[CH3:6])[CH3:2].Br[C:26]1[CH:33]=[CH:32][C:31]([C:34]([F:37])([F:36])[F:35])=[CH:30][C:27]=1[CH:28]=[O:29]>>[CH2:1]([O:3][C:4](=[O:24])[CH:5]([C:7]1[CH:8]=[C:9]([C:26]2[CH:33]=[CH:32][C:31]([C:34]([F:37])([F:36])[F:35])=[CH:30][C:27]=2[CH:28]=[O:29])[C:10]([O:13][CH3:14])=[CH:11][CH:12]=1)[CH3:6])[CH3:2]

Participants

3

Reactant 2

HCID 70180472-Bromo-5-(trifluoromethyl)benzaldehydeHCID 58120020HCID 58120020, compound

Product 1

HCID 86651114HCID 86651114, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 2-[4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-propionic acid ethyl ester and 2-bromo-5-(trifluoromethyl)benzaldehyde.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2b020491c93e463d89fd087dc5890f3d
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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