Ethylamine → HCID 66607287, compound

HRID 1810358Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:27])[CH:5]([C:7]1[CH:8]=[C:9]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH:25]=O)[C:10]([O:13][CH3:14])=[CH:11][CH:12]=1)[CH3:6])[CH3:2].[CH2:28]([NH2:30])[CH3:29]>>[CH2:1]([O:3][C:4](=[O:27])[CH:5]([C:7]1[CH:8]=[C:9]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:23])([F:24])[F:22])=[CH:17][C:16]=2[CH2:25][NH:30][CH2:28][CH3:29])[C:10]([O:13][CH3:14])=[CH:11][CH:12]=1)[CH3:6])[CH3:2]

Participants

Reactant 2

HCID 6341Ethylamine

HCID 86651114HCID 86651114, compound

Product 1

HCID 66607287HCID 66607287, compound

Procedure

Prepared according to the procedure described in Example 1, Step 5, using the following starting materials: 2-(2′-formyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-propionic acid ethyl ester and ethylamine (2M in THF).

Workup

customPrepared

Sources & evidence

ORD record: ord-f9953713e5464048828db52379416e75
Source dataset: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08362044B2

Reaction notes

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