Triethylamine → 1-(2,4-Dichlorophenyl)cyclopropanecarbonyl chloride

Participants

Role	Name	HCID	Charge
Reactant	Triethylamine	HCID 8471	—
Reactant	Oxalyl chloride	HCID 65578	—
Reactant	1-(2,4-Dichlorophenyl)cyclopropanecarboxylic acid	HCID 736103	—
Catalyst	Dimethylformamide	HCID 6228	—
Solvent	Dichloromethane	HCID 6344	—
Product	1-(2,4-Dichlorophenyl)cyclopropanecarbonyl chloride	HCID 3019290	—

Reaction Conditions

Temperature	0 °C

Reaction Steps

1-(2,4-Dichlorophenyl)-cyclopropanecarboxylic acid (0.086 g, 0.37 mmol) and triethylamine (0.08 mL, 0.56 mmol) were combined in CH2Cl2 (2 mL) and cooled to 0° C. Oxalyl chloride (0.05 mL, 0.56 mmol) was added, followed by DMF (3 drops), and the reaction was stirred for 20 minutes at 0° C. and then warmed to room temperature to give the title compound, which was used directly in the next step.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08362044B2
Source dataset	uspto-grants-2013_01
ORD ID	ord-3a9adcd817e642b085d37a10799320a8
Source note	uspto-grants-2013_01