Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810425Generated: October 25, 2026

Ethyl 2-(4-(benzyloxy)-3-bromophenyl)acetate → {6-Benzyloxy-2'-[(benzyloxycarbonyl-ethyl-amino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester

https://huagongshe.com/reaction/1810425

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(4-(benzyloxy)-3-bromophenyl)acetateHCID 18620085—
Reactant(Ethyl)[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethylbenzyl]carbamic acid benzyl esterHCID 66603618—
Product{6-Benzyloxy-2'-[(benzyloxycarbonyl-ethyl-amino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl esterHCID 66607697—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-carbamic acid benzyl ester and (4-benzyloxy-3-bromo-phenyl)-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362044B2
Source datasetuspto-grants-2013_01
ORD IDord-ece26eed185b4bb885d96110fb5cf9a9
Source noteuspto-grants-2013_01