2-Bromo-5-(trifluoromethyl)benzaldehyde → HCID 86633175, compound

HRID 1810431Notes

Reaction equation

HRID 1810431 reaction equation
[CH2:1]([O:3][C:4](=[O:29])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:8](B2OC(C)(C)C(C)(C)O2)[CH:7]=1)[CH3:2].Br[C:31]1[CH:38]=[CH:37][C:36]([C:39]([F:42])([F:41])[F:40])=[CH:35][C:32]=1[CH:33]=[O:34]>>[CH2:1]([O:3][C:4](=[O:29])[CH2:5][C:6]1[CH:7]=[C:8]([C:31]2[CH:38]=[CH:37][C:36]([C:39]([F:42])([F:41])[F:40])=[CH:35][C:32]=2[CH:33]=[O:34])[C:9]([O:12][CH2:13][C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 70180472-Bromo-5-(trifluoromethyl)benzaldehydeHCID 58149316HCID 58149316, compound

Product 1

HCID 86633175HCID 86633175, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: [4-benzyloxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester and 2-bromo-5-(trifluoromethyl)benzaldehyde.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6a51f8cf562b427d85e3f9ffa63d7f84
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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