Ethylamine → HCID 66607357, compound

HRID 1810467Notes

Reaction equation

[F:1][C:2]([F:26])([C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH:24]=O)[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[C:3]([OH:5])=[O:4].[CH2:27]([NH2:29])[CH3:28]>>[CH2:27]([NH:29][CH2:24][C:15]1[CH:16]=[C:17]([C:20]([F:21])([F:22])[F:23])[CH:18]=[CH:19][C:14]=1[C:8]1[C:9]([O:12][CH3:13])=[CH:10][CH:11]=[C:6]([C:2]([F:26])([F:1])[C:3]([OH:5])=[O:4])[CH:7]=1)[CH3:28]

Participants

Reactant 2

HCID 6341Ethylamine

HCID 86651119HCID 86651119, compound

Product 1

HCID 66607357HCID 66607357, compound

Procedure

Prepared according to the procedure described in Example 1, Step 5, using the following starting materials: difluoro-(2′-formyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid and ethylamine (2M in THF).

Workup

customPrepared

Sources & evidence

ORD record: ord-faa65d57aa234ffea62f1153ce82691b
Source dataset: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08362044B2

Reaction notes

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