Acetyl chloride → HCID 54674023, compound

HRID 1810469Notes

Reaction equation

HRID 1810469 reaction equation
[CH2:1]([O:3][C:4](=[O:35])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([NH2:20])=[CH:16][C:15]=2[CH2:21][N:22]([C:25]([O:27][CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[O:26])[CH2:23][CH3:24])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].[C:36](Cl)(=[O:38])[CH3:37]>>[CH2:1]([O:3][C:4](=[O:35])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([NH:20][C:36](=[O:38])[CH3:37])=[CH:16][C:15]=2[CH2:21][N:22]([C:25]([O:27][CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[O:26])[CH2:23][CH3:24])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 58148932(4'-Amino-2'-[(benzyloxycarbonyl-ethyl-amino)-methyl]-6-methoxy-biphenyl-3-yl)-acetic acid ethyl ester

Product 1

HCID 54674023HCID 54674023, compound

Procedure

Prepared according to the procedure described in Example 39, Step 1, using the following starting materials: {4′-amino-2′-[(benzyloxycarbonyl-ethyl-amino)-methyl]-6-methoxy-biphenyl-3-yl}-acetic acid ethyl ester and acetyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-90ab87157fdb40b1805253957b2d6737
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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