HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-5-fluoropyridine → [2'-[(tert-Butoxycarbonyl-ethyl-amino)-methyl]-4'-(5-fluoro-pyridin-2-yl)-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-5-fluoropyridine | HCID 2783171 | — |
| Reactant | [2'-[(Tert-butoxycarbonyl-ethyl-amino)-methyl]-6-methoxy-4'-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-3-yl]-acetic acid ethyl ester | HCID 58149092 | — |
| Product | [2'-[(tert-Butoxycarbonyl-ethyl-amino)-methyl]-4'-(5-fluoro-pyridin-2-yl)-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester | HCID 58148946 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: [2′-[(tert-butoxycarbonyl-ethyl-amino)-methyl]-6-methoxy-4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-3-yl]-acetic acid ethyl ester and 2-bromo-5-fluoropyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362044B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-f0b12f19a0cb4960a3b6f1c3d4c7e8cd |
| Source note | uspto-grants-2013_01 |