Ethylamine → (2'-Ethylaminomethyl-6'-methoxy-biphenyl-3-yl)-acetic acid methyl ester

HRID 1810487Notes

Reaction equation

HRID 1810487 reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:6]=[C:7]([C:11]2[C:16]([O:17][CH3:18])=[CH:15][CH:14]=[CH:13][C:12]=2[CH:19]=O)[CH:8]=[CH:9][CH:10]=1.[CH2:22]([NH2:24])[CH3:23]>>[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:6]=[C:7]([C:11]2[C:16]([O:17][CH3:18])=[CH:15][CH:14]=[CH:13][C:12]=2[CH2:19][NH:24][CH2:22][CH3:23])[CH:8]=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 6341EthylamineHCID 58149056HCID 58149056, compound

Product 1

HCID 58149181(2'-Ethylaminomethyl-6'-methoxy-biphenyl-3-yl)-acetic acid methyl ester

Procedure

Prepared according to the procedure described in Example 33, Step 4, using the following starting materials: (2′-formyl-6′-methoxy-biphenyl-3-yl)-acetic acid methyl ester and ethylamine (2M in THF).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2755d97e52cf41878b5aa9f0843fe781
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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