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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810503Generated: October 31, 2026

(4-Chlorophenyl)methyl chloroformate → (2'-{[(4-Chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-6-methoxy-5'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/1810503

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chlorophenyl)methyl chloroformateHCID 13292914—
Reactant(2'-Ethylaminomethyl-6-methoxy-5'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl esterHCID 66607502—
Product(2'-{[(4-Chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-6-methoxy-5'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl esterHCID 66607939—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-6-methoxy-5′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and 4-chlorobenzyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362044B2
Source datasetuspto-grants-2013_01
ORD IDord-fa6ce16a38974ba48b7dab6530f72624
Source noteuspto-grants-2013_01