Cyclopropanecarbonyl chloride → {2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-6-methoxy-4'-quinolin-6-yl-biphenyl-3-yl}-acetic acid ethyl ester

HRID 1810519Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1810519
[CH2:1]([O:3][C:4](=[O:34])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[C:22]4[C:27](=[CH:28][CH:29]=3)[N:26]=[CH:25][CH:24]=[CH:23]4)=[CH:16][C:15]=2[CH2:30][NH:31][CH2:32][CH3:33])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].[CH:35]1([C:38](Cl)=[O:39])[CH2:37][CH2:36]1>>[CH2:1]([O:3][C:4](=[O:34])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:21]=[C:22]4[C:27](=[CH:28][CH:29]=3)[N:26]=[CH:25][CH:24]=[CH:23]4)=[CH:16][C:15]=2[CH2:30][N:31]([C:38]([CH:35]2[CH2:37][CH2:36]2)=[O:39])[CH2:32][CH3:33])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

Komponenten

3

Edukt 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 58149185(2'-Ethylaminomethyl-6-methoxy-4'-quinolin-6-yl-biphenyl-3-yl)-acetic acid ethyl ester

Produkt 1

HCID 58148828{2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-6-methoxy-4'-quinolin-6-yl-biphenyl-3-yl}-acetic acid ethyl ester

Versuchsvorschrift

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-6-methoxy-4′-quinolin-6-yl-biphenyl-3-yl)-acetic acid ethyl ester and cyclopropanecarbonyl chloride.

Aufarbeitung

  1. customPrepared

Quellen und Nachweise

ORD-Eintrag
ord-1824192674bd45178183bafa0b7a51fd
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08362044B2

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