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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810528Generated: November 2, 2026

Methyl 2-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetate → {2'-[(Benzyloxycarbonyl-ethyl-amino)-methyl]-4-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

https://huagongshe.com/reaction/1810528

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetateHCID 22930398—
Reactant(2-Bromo-5-trifluoromethyl-benzyl)-ethyl-carbamic acid benzyl esterHCID 66604198—
Product{2'-[(Benzyloxycarbonyl-ethyl-amino)-methyl]-4-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl esterHCID 66608296—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: [2-methoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid methyl ester and (2-bromo-5-trifluoromethyl-benzyl)-ethyl-carbamic acid benzyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362044B2
Source datasetuspto-grants-2013_01
ORD IDord-9a683be3359747668a7ec851265c0836
Source noteuspto-grants-2013_01