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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810550Generated: October 29, 2026

Cyclopropanecarboxylic acid ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-amide → {2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-5,4'-bis-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

https://huagongshe.com/reaction/1810550

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarboxylic acid ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-amideHCID 66607375—
ReactantHCID 86651106HCID 86651106—
Product{2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-5,4'-bis-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl esterHCID 86651129—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: cyclopropanecarboxylic acid ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-amide and (3-trifluoromethanesulfonyloxy-5-trifluoromethyl-phenyl)-acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362044B2
Source datasetuspto-grants-2013_01
ORD IDord-731a96cd6c7f4bb9ab65e79e49950357
Source noteuspto-grants-2013_01