Methyl 2-(3-bromo-5-chlorophenyl)acetate → HCID 66607284, compound

HRID 1810552Notes

Reaction equation

HRID 1810552 reaction equation
[CH2:1]([N:3]([CH2:7][C:8]1[CH:13]=[C:12]([C:14]([F:17])([F:16])[F:15])[CH:11]=[CH:10][C:9]=1B1OC(C)(C)C(C)(C)O1)[C:4](=[O:6])[CH3:5])[CH3:2].[CH3:27][O:28][C:29](=[O:39])[CH2:30][C:31]1[CH:36]=[C:35]([Cl:37])[CH:34]=[C:33](Br)[CH:32]=1>>[CH3:27][O:28][C:29](=[O:39])[CH2:30][C:31]1[CH:32]=[C:33]([C:9]2[CH:10]=[CH:11][C:12]([C:14]([F:15])([F:16])[F:17])=[CH:13][C:8]=2[CH2:7][N:3]([C:4](=[O:6])[CH3:5])[CH2:1][CH3:2])[CH:34]=[C:35]([Cl:37])[CH:36]=1

Participants

3

Reactant 2

HCID 58149292Methyl 2-(3-bromo-5-chlorophenyl)acetateHCID 66608096N-ethyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-acetamide

Product 1

HCID 66607284HCID 66607284, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: N-ethyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-acetamide and (3-bromo-5-chloro-phenyl)-acetic acid methyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-8fbf58c31c784d9991b7aead5d81430a
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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