(4-Chlorophenyl)methyl chloroformate → HCID 66607367, compound
Reaction equation
[Br:1][C:2]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:3]=1[CH2:4][NH:5][CH2:6][CH3:7].Cl[C:17]([O:19][CH2:20][C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][CH:22]=1)=[O:18]>>[Cl:27][C:24]1[CH:23]=[CH:22][C:21]([CH2:20][O:19][C:17](=[O:18])[N:5]([CH2:4][C:3]2[CH:8]=[C:9]([C:12]([F:13])([F:14])[F:15])[CH:10]=[CH:11][C:2]=2[Br:1])[CH2:6][CH3:7])=[CH:26][CH:25]=1Participants
3
Procedure
Prepared according to the procedure described in Example 56, Step 2, using the following starting materials: (2-bromo-5-trifluoromethyl-benzyl)-ethyl-amine and 4-chlorobenzyl chloroformate.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-771fbe5381934623b027c97536c00140
- Source dataset
- uspto-grants-2013_01
- Patent number
- US08362044B2
Reaction notes
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