HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(3-bromo-5-chlorophenyl)acetate → (5-Chloro-2'-{[(4-chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(3-bromo-5-chlorophenyl)acetate | HCID 58149292 | — |
| Reactant | Ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-carbamic acid 4-chloro-benzyl ester | HCID 66607359 | — |
| Product | (5-Chloro-2'-{[(4-chloro-benzyloxycarbonyl)-ethyl-amino]-methyl}-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester | HCID 66607031 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-carbamic acid 4-chloro-benzyl ester and (3-bromo-5-chloro-phenyl)-acetic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362044B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-cd630d638af541479555ae4a397fbc68 |
| Source note | uspto-grants-2013_01 |