1-Chloro-4-(isocyanatomethyl)benzene → HCID 66607220, compound
Reaction equation
[Br:1][C:2]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:3]=1[CH2:4][NH:5][CH2:6][CH3:7].[Cl:16][C:17]1[CH:26]=[CH:25][C:20]([CH2:21][N:22]=[C:23]=[O:24])=[CH:19][CH:18]=1>>[Br:1][C:2]1[CH:11]=[CH:10][C:9]([C:12]([F:13])([F:14])[F:15])=[CH:8][C:3]=1[CH2:4][N:5]([CH2:6][CH3:7])[C:23]([NH:22][CH2:21][C:20]1[CH:25]=[CH:26][C:17]([Cl:16])=[CH:18][CH:19]=1)=[O:24]Participants
3
Procedure
Prepared according to the procedure described in Example 95, Step 1, using the following starting materials: (2-bromo-5-trifluoromethyl-benzyl)-ethyl-amine and 4-chlorobenzyl isocyanate.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-ed8e1e1692144055b2476023338d7d98
- Source dataset
- uspto-grants-2013_01
- Patent number
- US08362044B2
Reaction notes
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