Methyl 2-(3-bromo-5-chlorophenyl)acetate → HCID 66606870, compound

HRID 1810568Notes

Reaction equation

HRID 1810568 reaction equation
[Cl:1][C:2]1[CH:34]=[CH:33][C:5]([CH2:6][NH:7][C:8](=[O:32])[N:9]([CH2:30][CH3:31])[CH2:10][C:11]2[CH:16]=[C:15]([C:17]([F:20])([F:19])[F:18])[CH:14]=[CH:13][C:12]=2B2OC(C)(C)C(C)(C)O2)=[CH:4][CH:3]=1.[CH3:35][O:36][C:37](=[O:47])[CH2:38][C:39]1[CH:44]=[C:43]([Cl:45])[CH:42]=[C:41](Br)[CH:40]=1>>[CH3:35][O:36][C:37](=[O:47])[CH2:38][C:39]1[CH:40]=[C:41]([C:12]2[CH:13]=[CH:14][C:15]([C:17]([F:19])([F:18])[F:20])=[CH:16][C:11]=2[CH2:10][N:9]([CH2:30][CH3:31])[C:8]([NH:7][CH2:6][C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:34][CH:33]=2)=[O:32])[CH:42]=[C:43]([Cl:45])[CH:44]=1

Participants

3

Reactant 2

HCID 58149292Methyl 2-(3-bromo-5-chlorophenyl)acetateHCID 66607574HCID 66607574, compound

Product 1

HCID 66606870HCID 66606870, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 3-(4-chloro-benzyl)-1-ethyl-1-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-urea and (3-bromo-5-chloro-phenyl)-acetic acid methyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ebbdfd13ee6c44d693547d17d3b92045
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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