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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810571Generated: November 1, 2026

Methyl 2-(3-bromo-5-chlorophenyl)acetate → [5-Chloro-2'-(1-ethyl-3-methyl-ureidomethyl)-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl ester

https://huagongshe.com/reaction/1810571

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-bromo-5-chlorophenyl)acetateHCID 58149292—
Reactant1-Ethyl-3-methyl-1-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-ureaHCID 66607138—
Product[5-Chloro-2'-(1-ethyl-3-methyl-ureidomethyl)-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl esterHCID 66607666—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 1-ethyl-3-methyl-1-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-urea and (3-bromo-5-chloro-phenyl)-acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362044B2
Source datasetuspto-grants-2013_01
ORD IDord-d3f701217f84492cac2e0d9b0f6a5d9c
Source noteuspto-grants-2013_01