HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(3-bromo-5-chlorophenyl)acetate → {2'-[(Benzoyl-ethyl-amino)-methyl]-5-chloro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(3-bromo-5-chlorophenyl)acetate | HCID 58149292 | — |
| Reactant | N-ethyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-benzamide | HCID 66607577 | — |
| Product | {2'-[(Benzoyl-ethyl-amino)-methyl]-5-chloro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester | HCID 66607292 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: N-ethyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-benzamide and (3-bromo-5-chloro-phenyl)-acetic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362044B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-a19dfea5b6064cf18c80bc26816fa8c0 |
| Source note | uspto-grants-2013_01 |