2-Bromo-5-(trifluoromethyl)benzaldehyde → HCID 86651137, compound

HRID 1810575Notes

Reaction equation

HRID 1810575 reaction equation
[CH2:1]([O:3][C:4](=[O:22])[CH2:5][C:6]1[CH:11]=[C:10](B2OC(C)(C)C(C)(C)O2)[CH:9]=[C:8]([Cl:21])[CH:7]=1)[CH3:2].Br[C:24]1[CH:31]=[CH:30][C:29]([C:32]([F:35])([F:34])[F:33])=[CH:28][C:25]=1[CH:26]=[O:27]>>[CH2:1]([O:3][C:4](=[O:22])[CH2:5][C:6]1[CH:11]=[C:10]([C:24]2[CH:31]=[CH:30][C:29]([C:32]([F:35])([F:34])[F:33])=[CH:28][C:25]=2[CH:26]=[O:27])[CH:9]=[C:8]([Cl:21])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 70180472-Bromo-5-(trifluoromethyl)benzaldehydeHCID 58148831HCID 58148831, compound

Product 1

HCID 86651137HCID 86651137, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: [3-chloro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester and 2-bromo-5-(trifluoromethyl)benzaldehyde.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ed088afbcf764f5fb6b21b1e159c0052
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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