Ethylamine → HCID 66607703, compound

HRID 1810576Notes

Reaction equation

HRID 1810576 reaction equation
[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]1[CH:7]=[C:8]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH:23]=O)[CH:9]=[C:10]([Cl:12])[CH:11]=1)[CH3:2].[CH2:26]([NH2:28])[CH3:27]>>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]1[CH:7]=[C:8]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:20])([F:21])[F:22])=[CH:15][C:14]=2[CH2:23][NH:28][CH2:26][CH3:27])[CH:9]=[C:10]([Cl:12])[CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 86651137HCID 86651137, compound

Product 1

HCID 66607703HCID 66607703, compound

Procedure

Prepared according to the procedure described in Example 33, Step 4, using the following starting materials: (5-chloro-2′-formyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and ethylamine (2M in THF).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-0a3ea4d8e68f4c49a100d2ab5a78f30e
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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