2-Bromo-5-(trifluoromethyl)benzaldehyde → HCID 86651142, compound

HRID 1810588Notes

Reaction equation

HRID 1810588 reaction equation
Br[C:2]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:3]=1[CH:4]=[O:5].[CH3:14][O:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][C:23]#[N:24])=[CH:18][C:17]=1B1OC(C)(C)C(C)(C)O1>>[CH:4]([C:3]1[CH:6]=[C:7]([C:10]([F:13])([F:12])[F:11])[CH:8]=[CH:9][C:2]=1[C:21]1[C:16]([O:15][CH3:14])=[CH:17][CH:18]=[C:19]([CH2:22][C:23]#[N:24])[CH:20]=1)=[O:5]

Participants

3

Reactant 2

HCID 70180472-Bromo-5-(trifluoromethyl)benzaldehydeHCID 58148903HCID 58148903, compound

Product 1

HCID 86651142HCID 86651142, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 2-bromo-5-(trifluoromethyl)benzaldehyde and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetonitrile.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-de00388f98c94d228c7183c5bf20b28e
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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