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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1811221Generated: October 28, 2026

6-Amino-5-fluoroindolin-2-one → HCID 66608344, compound

https://huagongshe.com/reaction/1811221

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Amino-5-fluoroindolin-2-oneHCID 10103504—
Reactant3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 86637676—
ProductHCID 66608344HCID 6660834450%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 15 with 3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 5-fluoro-6-amino-1,3-dihydro-indol-2-one as starting materials to give 2-(6-amino-5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-morpholin-4-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (40 mg, 50%) as a red solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362251B2
Source datasetuspto-grants-2013_01
ORD IDord-0606f058c86b42348c3325a830a6e7b2
Source noteuspto-grants-2013_01