HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Amino-5-fluoroindolin-2-one → HCID 66608553, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Amino-5-fluoroindolin-2-one | HCID 59250054 | — |
| Reactant | 3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde | HCID 86637676 | — |
| Product | HCID 66608553 | HCID 66608553 | 43.8% |
Reaction Steps
The title compound was prepared under the same conditions as described in Example 15 with 3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 5-fluoro-7-amino-1,3-dihydro-indol-2-one as starting materials to give 2-(7-amino-5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-morpholin-4-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (35 mg, 43.8%) as a red solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362251B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-fcad39662b1a4db693a846679ba658e6 |
| Source note | uspto-grants-2013_01 |