HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(tert-butoxycarbonyl)glycine → N-Boc-glycyl-L-proline benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(tert-butoxycarbonyl)glycine | HCID 78288 | — |
| Reactant | Proline benzyl ester hydrochloride | HCID 2733413 | — |
| Reactant | (S,R)-1-(2-tert-butoxycarbonylamino-2-phenylacetyl)-pyrrolidine-2-carboxylic acid benzyl ester | HCID 15288611 | — |
| Product | N-Boc-glycyl-L-proline benzyl ester | HCID 13152016 | — |
Reaction Steps
Compound 26 was synthesized from N-Boc-glycine and L-proline benzyl ester hydrochloride, following the procedure as described for compound 2a, as a white crystallized solid. MS (ESI, EI+) m/z=363 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362068B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-2a0896929146424d85655d3353ccbb46 |
| Source note | uspto-grants-2013_01 |