HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → N-(6-Methoxypyridin-3-YL)-3-(2-methyl-6-(methylsulfinyl)pyrimidin-4-YL)pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | N-(6-methoxypyridin-3-yl)-3-(2-methyl-6-(methylthio)pyrimidin-4-yl)pyrazin-2-amine | HCID 66599972 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | N-(6-Methoxypyridin-3-YL)-3-(2-methyl-6-(methylsulfinyl)pyrimidin-4-YL)pyrazin-2-amine | HCID 66600383 | — |
Reaction Steps
A glass microwave reaction vessel was charged with N-(6-methoxypyridin-3-yl)-3-(2-methyl-6-(methylthio)pyrimidin-4-yl)pyrazin-2-amine (11 mg, 0.032 mmol) and 3-chloroperoxybenzoic acid (11.15 mg, 0.065 mmol) in dioxane (1 mL). The reaction mixture was stirred at room temperature for 1 h. The reaction mixture was used for the next step reaction without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362241B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-f943368860b442f8a3e4096d9671e705 |
| Source note | uspto-grants-2013_01 |