Methyl iodide → 3-Methyl-1-[methyl(propan-2-yl)carbamoyl]-1H-imidazol-3-ium iodide

HRID 1812403Notes

Reaction equation

HRID 1812403 reaction equation
[CH:1]([N:4]([CH3:12])[C:5]([N:7]1[CH:11]=[CH:10][N:9]=[CH:8]1)=[O:6])([CH3:3])[CH3:2].[C:13](#N)C.[I:16]C>>[I-:16].[CH:1]([N:4]([CH3:12])[C:5]([N:7]1[CH:11]=[CH:10][N+:9]([CH3:13])=[CH:8]1)=[O:6])([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 6342AcetonitrileHCID 66611115N-isopropyl-N-methyl-1H-imidazole-1-carboxamide

Product 1

HCID 431454203-Methyl-1-[methyl(propan-2-yl)carbamoyl]-1H-imidazol-3-ium iodide

Procedure

To a 50 mL round-bottomed flask was added N-isopropyl-N-methyl-1H-imidazole-1-carboxamide (0.550 g, 3.29 mmol), acetonitrile (29 mL, 3.29 mmol), iodomethane (0.817 mL, 13.16 mmol). The resulting solution was stirred at room temperature overnight. The solvent was removed under vacuum to afford 1-(isopropyl(methyl)carbamoyl)3-methyl-1H-imidazol-3-ium iodide.

Workup

  1. customThe solvent was removed under vacuum

Sources & evidence

ORD record
ord-f64ad7eb404c44cf8b9b49f2f03af735
Source dataset
uspto-grants-2013_01
Patent number
US08362241B2

Reaction notes

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