Acetate → 4-methoxy-N-(4-nitrophenyl)aniline

HRID 181251Notes

Reaction equation

HRID 181251 reaction equation
[Br:47][c:48]1[cH:49][cH:50][c:51]([N+:54](=[O:55])[O-:56])[cH:52][cH:53]1.[C:72]([O-:73])(=[O:74])[CH3:75].[C:77]([O-:78])(=[O:79])[CH3:80].[CH3:57][O:58][c:59]1[cH:60][cH:61][c:62]([NH2:63])[cH:64][cH:65]1.[O:66]1[CH2:67][CH2:68][O:69][CH2:70][CH2:71]1.[Pd+2:76].[cH:1]1[cH:2][cH:3][c:4]([P:5]([c:6]2[cH:7][cH:8][c:9]3[c:10]([cH:11][cH:12][cH:13][cH:14]3)[c:15]2-[c:16]2[c:17]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[cH:23][cH:24][c:25]2[P:26]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:45][cH:46]1>>[c:48]1([NH:63][c:62]2[cH:61][cH:60][c:59]([O:58][CH3:57])[cH:65][cH:64]2)[cH:49][cH:50][c:51]([N+:54](=[O:55])[O-:56])[cH:52][cH:53]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 7732P-AnisidineHCID 114661-Bromo-4-nitrobenzeneHCID 312751,4-DioxaneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 634876Binap, (A+-)-

Product 1

HCID 27480234-methoxy-N-(4-nitrophenyl)aniline

Sources & evidence

ORD record
ord-75c2759ccf3a447cafc7b3f41ab9ffdb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…