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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1813267Generated: November 2, 2026

2,6-Lutidine → HCID 178444630, compound

https://huagongshe.com/reaction/1813267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-LutidineHCID 7937—
Reactant2-Bromo-4'-(trifluoromethyl)acetophenoneHCID 321979—
ReactantHept-6-ynalHCID 11355455—
CatalystHCID 13902521HCID 13902521—
Catalyst(R)-alpha,alpha-Bis(3,5-bis(trifluoromethyl)phenyl)-2-pyrrolidinemethanol trimethylsilyl etherHCID 16218311—
SolventDimethylformamideHCID 6228—
ProductHCID 178444630HCID 178444630—
ProductHCID 178444631HCID 178444631—

Reaction Conditions

Temperature22 °C

Provenance & Evidence

DOI10.1038/s41467-023-42446-5
Source datasetDataset from `Ultra-high-throughput mapping of the chemical space of asymmetric catalysis enables accelerated reaction discovery`
ORD IDord-a2fe7087fd2d4ee2b8df30646453b95d
Source noteDataset from `Ultra-high-throughput mapping of the chemical space of asymmetric catalysis enables accelerated reaction discovery`