2-(4-Chlorobenzenesulfonyl)acetonitrile → HCID 22504466, compound
Reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([CH3:9])=[CH:4][C:3]=1[S:10]([CH2:13][C:14]#[N:15])(=[O:12])=[O:11].ClC1C=C[C:20]([S:23]([CH2:26]C#N)(=[O:25])=[O:24])=CC=1>>[Cl:8][C:6]1[C:5]([CH3:9])=[CH:4][C:3]([S:10]([C:13](=[C:26]([S:10]([CH3:3])(=[O:12])=[O:11])[S:23]([CH3:20])(=[O:25])=[O:24])[C:14]#[N:15])(=[O:12])=[O:11])=[C:2]([CH3:1])[CH:7]=1Participants
3
Procedure
The titled compound was prepared in an analogous fashion to Intermediate 2 except that 2-(2,5-dimethyl-4-chlorobenzenesulfonyl) acetonitrile was utilized in place of 2-(4-chlorobenzenesulfonyl) acetonitrile.
Sources & evidence
- ORD record
- ord-c51a08c96def4abdb8ee5877aad2383a
- Source dataset
- uspto-grants-2005_04
- Patent number
- US06875771B2
Reaction notes
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