2-Chloroethyl methyl sulfide → (Z)-4-[4-(2-Methylsulfanylethoxy)phenyl]-3,4-diphenyl-but-3-en-1-ol

HRID 1813933Notes

Reaction equation

HRID 1813933 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[C:9]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:10][CH2:11][OH:12])=[CH:4][CH:3]=1.[CH3:25][S:26][CH2:27][CH2:28]Cl>>[CH3:25][S:26][CH2:27][CH2:28][O:1][C:2]1[CH:3]=[CH:4][C:5](/[C:8](/[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[C:9](\[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)/[CH2:10][CH2:11][OH:12])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 109652-Chloroethyl methyl sulfideHCID 539701334-(4-Hydroxy-1,2-diphenylbut-1-en-1-yl)phenol

Product 1

HCID 20720965(Z)-4-[4-(2-Methylsulfanylethoxy)phenyl]-3,4-diphenyl-but-3-en-1-ol

Procedure

The compound is prepared by using the method described in the example 1a starting from 4-(4-hydroxyphenyl)-3,4-diphenyl-but-3-en-1-ol (preparation described in U.S. Pat. No. 4,996,225) and 2-chloroethyl methyl sulfide.

Workup

  1. customThe compound is prepared
  2. custompreparation

Sources & evidence

ORD record
ord-b9edb49a1db74599ab9f52df0c1b9108
Source dataset
uspto-grants-2005_04
Patent number
US06875775B2

Reaction notes

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