Triethylamine → HCID 59996393, compound

Participants

Reaction Steps

Methoxyacetyl chloride (6 mL, 0.067 mmol) was added to a cooled (0° C.) solution of N-({(5S)-3-[4-(3,6-diazabicyclo[3.1.0]hex-3-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide (15 mg, 0.05 mmol) in triethylamine (14 μL, 0.10 mmol) and dichloromethane (1.0 mL). After 1 hour, the solution was diluted with dichloromethane, and washed with dilute NaHCO3, brine, and dried (MgSO4), filtered and concentrated. Purification by pTLC (5% MeOH—CH2Cl2) provided the title compound.

Provenance & Evidence