HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 11155683, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | (6-Hydroxy-benzo[b]thiophen-3-yl)acetic acid methyl ester | HCID 20765985 | — |
| Reactant | HCID 22280095 | HCID 22280095 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | 2-Oxopropiononitrile | HCID 69430 | — |
| Product | HCID 11155683 | HCID 11155683 | 62% |
Reaction Steps
Compounds 5C, 5E and cesium carbonate in 10 mL AcCN stirred at 60° C. for 18 hours. The reaction was then cooled, diluted with Et2O and filtered through Celite®. The filtrate was collected and concentrated in vacuo. Recrystalisation from CHCl3/Hexanes gave 340 mg (62%) of the title compound. MS m/z 487 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06875780B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-67e6a40856ba481795e547fdc7d096cc |
| Source note | uspto-grants-2005_04 |