3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazole → HCID 11188766, compound

HRID 1814155Notes

Reaction equation

HRID 1814155 reaction equation
C[O:2][C:3](=[O:15])[CH2:4][C:5]1[C:6]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][C:7]=2[S:8][CH:9]=1.Cl[CH2:17][C:18]1[CH:22]=[C:21]([C:23]2[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=2)[O:20][N:19]=1>>[Cl:29][C:26]1[CH:25]=[CH:24][C:23]([C:21]2[O:20][N:19]=[C:18]([CH2:17][O:14][C:11]3[CH:12]=[CH:13][C:6]4[C:5]([CH2:4][C:3]([OH:2])=[O:15])=[CH:9][S:8][C:7]=4[CH:10]=3)[CH:22]=2)=[CH:28][CH:27]=1

Participants

3

Reactant 2

HCID 14811003-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazoleHCID 20765985(6-Hydroxy-benzo[b]thiophen-3-yl)acetic acid methyl ester

Product 1

HCID 11188766HCID 11188766, compound

Procedure

The title compound was prepared from compound 5C and commercially available 3-chloromethyl-5-(4-chloro-phenyl)-isoxazole in the manner analogous to example 5F. MS m/z 414 (M+1).

Sources & evidence

ORD record
ord-85d06ca4b63d475f9c4fed0ee578d230
Source dataset
uspto-grants-2005_04
Patent number
US06875780B2

Reaction notes

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